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In the meantime, non-adjusted dosing in the first 1 to 2 days of antibiotic therapy during continuous renal replacement therapy followed by dose reduction later on seems to be a prudent approach.
After multiple dosing in the first cycle of therapy, no significant accumulation was observed, as the GMRs of AUC0 ∞ and Cmax (C1D3 vs. C1D1) were 1.23 and 1.20 in the 1 μg/kg dose group and 1.14 and 1.00 in the 2 μg/kg dose group, respectively.
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Identify applications and utility of serum markers dosed in the first trimester in predicting, early diagnosis and management of various complications of pregnancy.
However, two subjects were excluded because of serious irregularities: one received the same treatment in both periods and the other provided dates of dosing in the second treatment period that were earlier than those in the first treatment period.
Children are supposed to get four doses in the first 15 months of life.
Given that patients need six doses in the first year and three per year after that, it means the drug costs $750,000 in the first year and $375,000 thereafter.
As a result, doctors' purchases of Oxycodone, which reached 32.2 million doses in the first six months of 2010, fell by 97percentt in the same period this year.
The explosion of reactor four on 26 April 1986 killed dozens of plant staff and rescue workers, and led to high radiation doses in the first weeks and months that had significant effects on animal health and reproduction around Chernobyl.
Given that patients need six doses in the first year and three per year after that, it means the drug costs $750,000 per patient in the first year and $375,000 annually thereafter.
But although Merck managed to ship two million doses in the first half of this year, more than in any previous full year, Zostavax is once more in scant supply.
Because most of the resuspended Fel d 1 mass initially consisted of coarse particles, 77% by mass of the total cumulative dose in the first 30 min after a disturbance was predicted to deposit in the nose.
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