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Once-daily dosing has been suggested to benefit patients.
Clinically, metronomic S-1 dosing has been approved for the standard first- and second-line treatment of metastatic or advanced stage of colorectal (CRC).
The PTH1R is a major target for new osteoporosis treatments, as pulsatile PTH dosing has been shown to induce net bone formation in both animals and humans, and PTH(1 34) was recently FDA approved for the treatment of post-menopausal osteoporosis.
A pharmacogenetic approach for accurate warfarin dosing has been developed based on known variations in VKORC1 and CYP2C9 genes [50].
Administration of DCU formulated in DMSO/corn oil (3 mg/kg, interperitoneal dosing) has been demonstrated to lower blood pressure in the spontaneously hypertensive rat (SHR) model [15].
Administration of fibrinogen concentrate, often guided by point-of-care viscoelastic testing to allow individualized dosing, has been successfully used as hemostatic therapy in a range of clinical settings, including cardiovascular surgery, postpartum hemorrhage, and trauma.
Similar(33)
Since the initial availability of antibiotics, methods to optimize antibiotic dosing have been explored [17, 73].
In adults, daily and twice-daily dosing have been used to good effect.
Since the initial availability of antibiotics, methods to optimize antibiotic dosing have been explored [ 17, 73].
Minimal data regarding the use of cystatin C-based medication dosing have been published.
She will be released once the medication dose has been established.
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