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Since it was our aim to propose a simple dosing guideline calculation for clinical practice, in the final individual dosing equation figures have been rounded off.
Traditional one-for-all dosing guideline of enrofloxacin is not applicable any more.
Thus, serum PK/PD parameters were the major data that was based to draw a dosing guideline here (Table 6 and Figure 4).
The CPOE doses showed 51.1% (120/235) compliance to the recommended initial dosing guideline compared with 34.9% in the pre-CPOE doses (82/235, p<0.001).
To develop a dosing guideline that accounts for variation in each of these parameters as well as in RRT modalities and settings, a large multicenter RRT pharmacokinetic study is required.
dEmpiric starting doses range from 3 to 5 mg/day [ 36, 37]; FDA therapeutic dosing guideline table ranges: low dose (0.5 to 2 mg/day), intermediate dose (3 to 4 mg/day) and high dose (5 to 7 mg/day).
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This is insufficiently anticipated by currently recommended dosing guidelines.
Rational dosing guidelines for drugs in pediatrics are urgently needed.
To study the adherence of rheumatologists to the hydroxychloroquine (HCQ) dosing guidelines established by the American Academy of Ophthalmology in 2011 and 2016.
http://ctdbase.org PharmGKB Database of drug information including dosing guidelines, drug labels, signaling pathway diagrams, drug-gene associations, and drug-phenotype relationships.
As a consequence, there are no definitive dosing guidelines that can be used for all critically ill patients who undergo CRRT.
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