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To examine the effects of computerized requests for pharmacist-to-dose (PTD), an advanced clinical decision support tool for dosing guidance, on antimicrobial therapy with vancomycin and aminoglycosides, describe PTD request utilization, and identify factors that may prolong this process.
Furthermore, this review serves to highlight the need for well-designed and conducted clinical and laboratory-based studies to provide the data from which robust dosing guidance can be developed to improve clinical outcomes in this most unwell cohort of patients.
These are likely the best reflection of current information regarding dosing guidance in pediatrics.
Figure 4B is the view projected after the dosing guidance menu button is selected.
Deriving optimal dosing guidance for children continues to be a concern for pediatric caregivers[ 29].
In addition, gentamicin and vancomycin dosing guidance was the same preintervention and postintervention.
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For the pediatric population, we developed a high‐dose methotrexate dashboard that is ultimately envisioned as a web‐based environment that will provide global users with the ability to: (i) register their patient data; (ii) view dosing transactions based on institution/caregiver‐specific criteria in real time; (iii) forecast future outcomes; and (iv) adhere to protocol‐specific dosing guidances.
In practice, however, the modified Fibonacci sequence, the most popular dose-escalation guidance scheme in dose-seeking phase I trials is a term which is too vague and should be avoided.
To investigate equivalent regimens for hypofractionated stereotactic radiotherapy (HSRT) for brain tumor treatment and to provide dose-escalation guidance to maximize the tumor control within the normal brain tolerance.
Instead, it was the "humble" figure of the blogger, working at home or in stolen hours at the office, who became your go-to person for the latest sounds - mp3 blogs are essentially music stores where the music is free, and in the case of Antiquiet and many others, served with a healthy dose of guidance, criticism and opinion untainted by commercial or PR imperatives.
In addition, no dose-selection guidance from biomarker or clinical signs are available in healthy volunteers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com