Sentence examples for dosing determinations from inspiring English sources

Therefore, development of nisin as a cancer therapeutic can be readily pursued following dosing determinations.

Patients treated with 5 mg/kg or 10 mg/kg TCZ showed significant improvement by week 2. The next dosing determination trial was conducted in Japan.

Higher preheats, up to 300 °C, preferentially removed OSL and TTOSL signals evident at longer stimulation times: those that remained yielded growth in signal with dose to approximately 10 kGy, but the accuracy of retrospective dose determinations was variable.

Compensating for this energy dependence of the absorbed dose determinations obtained from OSL in NaCl would thus require an energy-dependent conversion factor for photon energies below 600 keV.

For the single-dose determinations, all patients received MTS 10 mg/9 h or OROS methylphenidate 18 mg/day.

To complicate dose determinations, there is an apparent lack of dose proportionality that may be related to reduced drug availability or altered distribution with increasing dose (55).

In the pilot low dose determination study, 2.5 mg of oseltamivir was determined to be the low dose.

Data from the acute toxicity study may (a) serve as the basis for classification and labelling; (b) provide initial information on the mode of toxic action of a substance; (c) help arrive at a dose of a new compound; (d) help in dose determination in animal studies; and (e) help determine LD50 values that provide many indices of potential types of drug activity [ 5].

To determine a low oseltamivir dose exhibiting PK linearity, a pilot low dose determination investigation (n = 4) was performed using a single administration dose-escalation study.

Thus, a precise dose-determination is realised.

Therefore, dose determination and dose delivery are vital factors in controlling variability.