Sentence examples for dosing cycle from inspiring English sources

All in all, this new NSC design provides a convenient mean to set up a clinically more appealing weekly or longer dosing cycle for siRNA therapy, which addresses a significant unmet need for prostate cancer treatment and is potentially useful for other chronic disease conditions as well.

AMG 900 was administered through gavage on days 1 and 2 of each dosing cycle.

A very low pUA mobilizes urate from tophi, and maintaining uricase in plasma throughout the dosing cycle ensures its degradation.

A 32-year-old female with type 1 diabetes mellitus, who was one of two kidney/pancreas recipients, had a duodenal perforation during her second dosing cycle, which led to loss of her pancreas graft and withdrawal from the trial.

Generally, serum concentrations can be checked at any time in the dosing cycle as the change in PB concentrations through a daily dosing interval is not therapeutically relevant once steady-state has been achieved [ 62, 70].

No change was observed from first to second dosing cycle (Fig.  2b).

Both isotypes decreased after the first dose of pegloticase, then recovered during dosing cycles 2 and 3, and rose further as pUox declined in cycles 4 and 5.

With two dosing cycles 6 12 months apart, the number of visits increases to 30 40 during the initial 2 years postdiagnosis, clearly more than the 8 10 visits for insulin therapy required by current clinical standards of care.

Of the 18 patients who were assessed for toxicities, 5 (27.8%) received at least one fully dosed cycle, 2 (11.1%) of whom received fully dosed cycles for all cycles administered.

Of the 18 patients who were assessed for toxicities, 5 (27.8%) received at least one fully dosed cycle, 2 (11.1%) of whom had all cycles fully dosed.

Samples were collected prior to dosing on Days 1 and 4 and on Day 10 of both dosing cycles.