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Among patients who experienced an adverse event after statin rechallenge, the majority (64%) were being treated with intermittent, nondaily dosing at the time of the adverse event.Although musculoskeletal symptoms are reported by 90% of patients with statin intolerance, symptoms involving other organ systems may be more frequent than previously supposed.
Subjects oral cavities were examined for buccal irritation prior to dosing, at the time of lozenge dissolution, at 15, 30, 60, and 120 min post-dissolution and at discharge.
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Dosing at the appropriate time of the day may be an effective strategy to modulate the delivery of P-gp substrates to the brain.
Patients in the placebo group received an equal number of tablets, dosed at the same time of day as for the test compound and all containing placebo.
S began the Lexical Salience Task 90 min after dosing, at which time the subjective behavioral effects of oral AMPH are maximal (Brauer et al, 1996).
Patients on Pravachol, or pravastatin, were given half that dose, 40 milligrams a day, because that was the maximum allowable dose at the time.
The OV was introduced into the rumen as a pulse dose at the time of feeding, thus most likely having larger effect on methane production during the period when methane data were collected.
"Giving radiotherapy in a single dose at the time of surgery potentially offers a huge benefit, especially if it means fewer visits to hospital.
To further examine this question, we estimated the role of exogenous insulin by correlating insulin infusion dose at the time of the biopsy with Akt phosphorylated at T308, our most upstream target.
#Daily dose at the time point of each MRI imaging study.
The patients with sepsis had a lower MAP and higher norepinephrine dose at the time of the ACTH test.
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CEO of Professional Science Editing for Scientists @ prosciediting.com