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Foam protection requires additional plant components and measuring equipment (e.g., foam sensors, foam traps, and dosing apparatus for anti-foaming agents inside the fermenter, as well as a foam outlet in the subsequent stages of sludge storage [29, 31]).
If a method development study exhibits highly variable results (e.g., high%RSD) or lower than desired percentage recovery values, various parameters should be assessed prior to proceeding to validation including but not limited to the following: (1) container composition; (2) protection from light; (3) temperature; (4) filter bias; (5) dosing apparatus, and (6) stability.
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Dose apparatus and injection site were checked for dose residue using a scintillation probe.
This apparatus is composed of a core holder, a pressure transducer, dosing pumps for injecting formation waters and inhibitors into the core samples, an oven, a vacuum pump, and a brine collection tank.
Dosing solutions of PFOA dissolved in deionized water were analyzed from animal-watering apparatus to ensure no appreciable losses of PFOA occurred between changing solutions.
dosing regimen.
Shiga toxin made its way to the Golgi apparatus in control cells but not in cells dosed with manganese.
Perfectly dosed.
A 10 ml sodium chloride 0.9% flush per dose ensured no dose residue in any of the apparatus.
The possible sources of error in the radiometric method include both the HPLC apparatus and the dose calibrator used for measuring carrier and radioactivity, respectively.
Before LC-MS/MS analysis, each radiotracer was also analyzed by the calibrated radiometric method (activity using an ionization chamber dose calibrator and mass using HPLC apparatus) regularly used in our laboratory for quality control.
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