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Dosimetry with plastic scintillators is an interesting alternative for the measurement of the absorbed dose.
A good correlation of predictive MAA SPECT-based dosimetry with post-radioembolization Y-90 PET dosimetry was demonstrated in [15].
Personal dosimetry with routine TLD monitoring did not reveal an increase in radiation exposure to the body.
This code is called Neutron Spectrometry and Dosimetry with Artificial Neural networks unfolding code that was designed in a graphical interface.
While the 111In-pentetreotide surrogate approach appears reasonably good for estimating renal and blood dosimetry for 90Y-DOTATOC, tumor dosimetry with this approach is likely somewhat less accurate.
This is, for example, the case for pre-therapeutic dosimetry with 177Lu treatment of neuroendocrine tumors [17], administrated by intravenous injections.
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Here, we present murine whole-body biodistribution and pharmacokinetics of 64Cu-MM-302, as well as rodent and primate kidney micro-dosimetry, with biodistribution data extrapolated to predict human 64Cu-MM-302 dosimetry.
A biodistribution and radiation dosimetry study with 10 patients with lung cancer or lymphoma confirmed the excretion route with the highest activity found in kidneys and urinary bladder [ 64].
A comparison is made with previous mouse dosimetry and with other human studies employing different RGD-based radiopharmaceuticals.
Dosimetry studies with Lu-DOTATATE as well as the limited side effects with additional cycles of Lu-DOTATATE suggest that more cycles of Lu-DOTATATE can be safely given.
In vivo dosimetry performed with diodes is a reliable method for patient dose control [1].
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