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Our studies have shown that radiation treatment accuracy expressed as a comparison between calculated doses (by TPS) and measured doses (by TLD dosimetry) can be accurately predicted for tangential treatment of the chest wall after mastectomy.
Without the involvement of a medical physicist, the likelihood that dosimetry can be undertaken is probably low.
For example, pre-treatment dosimetry can be used to adjust the individual therapy dose, or even be used to select the most suitable radionuclide for therapy.
For 90Y microspheres, the risks for radiation-induced liver disease are of clinical concern, and at the same time, patient-specific dosimetry can be accomplished using only one patient scan [14].
In order to avoid toxicity due to absorbed radiation dose, dosimetry can be performed.
Further improvements in the performance of these cameras, and hence dosimetry, can be foreseen.
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The results clearly indicate that dosimetry models can be effectively used to a priori determine the laboratory conditions necessary for animals tests to accurately mimic human conditions.
Accurate comparisons between dosimetry models can be achieved by using the same input patient data (administered activity and SPECT/CT images) into all of the VBDM.
The inserts developed in this work provide unique SPECT imaging data, with activity distributions matching the underlying mathematical models for MRT dosimetry, which can be used to validate all approaches to SPECT activity quantification.
The volume receiving more than 40 Gy is reduced by 20% using conformal radiotherapy and there is a further 45% reduction using IMRT, demonstrating the dramatic improvement in dosimetry that can be achieved with this technique.
With the use of low-energy γ-rays at 208 and 113 keV emitted by Lu, concomitantly with the therapeutic β-radiation, not only can posttreatment scans be acquired, but patient dosimetry can also be performed.
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