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By not comparing TC to other active interventions that might offer comparable doses of weight bearing, or resistance and flexibility training, we cannot ascribe which aspect(s) of TC contributed to its therapeutic effects.
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NBC filled with cycling, volleyball and a heavy dose of weight lifting.
Potential interactions between dose of lisinopril, weight and renal function will be explored after the study is completed.
As outcome measures, we considered HbA1c, frequency of hypoglycaemia (especially if severe), glycaemic excursions (including post-prandial hyperglycaemia), total daily dose of insulin, weight change, changes in cardiovascular risk factors, and other adverse events.
Studies in rats have reported a dose-dependent reduction of weight gain.
Oral doses of 40/kg body weight of acetaminophen have been used for post-operative pain treatment in infants [ 9].
So we tried two different doses of AgNP/clay (1% weight versus 0.1% weight) to survey the dose-dependent response.
We also documented the type and dose (total and dose per kg of dosing body weight) of antimicrobials administered on the first day.
In most other cases, doses were reduced because of weight loss resulting in decreased body surface area.
Then, in the PRESCO trial, a higher dosing of ribavirin (weight-based dosing with 1000 to 1200 mg) was associated with better SVR rates but higher risk of anemia [ 25].
Finally, adjusting the dose for weight, as we have done, or measuring the medication serum concentration could increase the sensitivity of dose as a predictor of weight gain.
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