Sentence examples for doses capable of from inspiring English sources
In contrast, individual compounds administered at optimal monotherapy doses, capable of effective tumor growth inhibition (Supplementary Fig. S6C) resulted in considerable body weight loss.
22 Similarly, no blood pressure lowering effect of pravastatin at doses capable of effectively improving the lipid profile was reported by a recent analysis of the Cholesterol and Recurrent Events (CARE) trial.
Consistent with the notion that hepatitis is a major cause of liver cirrhosis (Poynard et al., 2001), the present data demonstrate that at doses capable of inhibiting hepatic inflammation, daumone effectively inhibits fibrosis.
MA has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the AR and the ER in the body [ 97– 97].
cocaine dose capable of changing mood and physiological parameters [21].
Both observations suggest that pharmacodynamic dosing, based on delivering a dose capable of producing a certain level of toxicity, may be superior to standard dosing.
In studies of treatment efficacy, similar methodology is employed aiming to identify a dose capable of producing a given rate of success.
It will be critical to determine the lowest dose capable of normalizing cerebellar morphology and improving hippocampal function while avoiding effects on the craniofacial skeleton.
Coagulation activity was confirmed after incubation of different concentrations of B. mattogrossensis crude venom with plasma in which the minimum coagulation dose capable of promoting coagulation in less than 1 min was 0.325 μg of protein.
This suggests that the SOD1 inhibition in blood pellets will be indicative of antiangiogenic activity, since when a dose capable of inhibiting blood cell SOD1 is achieved the threshold for antiangiogenic activity would have been crossed.
Bollag et al (2010) has previously shown that in order for the BRAF inhibitor vemurafenib to elicit a proper clinical response in melanoma, a dose capable of inhibiting BRAF by >80% was needed.
