Sentence examples for dosed twice from inspiring English sources

Once-daily MSER approaches maximum morphine concentration more quickly, approximates maximum concentration longer, and demonstrates less fluctuation in morphine concentration during a 24-hour period than CRM dosed twice daily.

For growth curves, mice were dosed twice daily with AZD8186 (50 mg/kg) and measured twice weekly using Vernier callipers.

Animals were dosed twice daily (8 am and 8 pm).

Stimulant medication was Dextroamphetamine dosed twice daily.

Furthermore, timolol 0.5% was dosed twice daily in the TS.

A double dummy design was used in which placebo was also dosed twice daily.

This design was necessary, however, as detemir was dosed twice-daily with a separate titration target before dinner.

This difference has been attributed to the twice-daily dosing of detemir (9), but NPH dosed twice-daily does not lead to dose escalation (1).

In a Phase 3 trial in CF patients designed to support regulatory filing in Europe and Canada, once-daily ARIKACE met the primary endpoint of non-inferiority to inhaled tobramycin solution dosed twice-daily (12).

11 In this study, once-daily elvitegravir with boosted ritonavir achieved a higher trough concentration compared to elvitegravir dosed twice-daily without boosting, achieving ≥3-fold inhibitory quotient (using protein-binding adjusted IC50).

It has also been suggested that bronchodilators with long durations of action provide a relatively consistent improvement in airway calibre over time, in contrast to the peaks and troughs that can arise with bronchodilators that are dosed twice-daily [ 22].