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Thus, there was a direct dose-response correlation between the level of bacterial phagocytosis and the amount of RACK1.
An inverse dose-response correlation of exogenously expressed ISG15 and release of Human Immunodeficiency Virus (HIV) virions is also found and suppression of ISG15 expression by siRNA counteracts IFN-mediated inhibition of HIV virion release [25].
We measured the viral reporter gene induction at early time points (4 and 8 h post infection with HSV-1 and 14 and 24 h post infection with HCMV) and observed a clear dose-response correlation.
A good dose-response correlation could be detected for compound 109, with a 4- to 9-fold upregulation of frataxin mRNA at the highest tested concentration of 10 µM.
The dose-response correlation between differing levels of physical activity and depression symptoms is not very clear.
This model is able to reveal important features of dose-response curves describing cell survival especially transitions from low to high doses in a dose-response correlation.
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Dose-response correlations will then be examined according to structural and functional regions.
The data presented here are consistent with positive dose-response correlations.
This subsequent analysis of co-registered dose and image data will be undertaken in several ways: i. Methods will be developed to assess dose-response correlations as a function of spatial position across each kidney (sampled at varying resolutions).
Most genes did not display a desired dose response correlation associated with usable biomarkers, but did support responses within the suite of genes investigated, somewhat validating their use within a broader biomarker approach.
There was no dose response correlation between the amount of C57BL/6J DNA added to the assay tube and the fluorometric response observed with the Taqman real-time PCR machine at 500 μM (data not shown) and the effect of changing the probe concentration from that recommended by the manufacturer (11) was not investigated further.
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