The thickness of a spherical-type neutron dose monitor has been optimized in order to obtain improved dose response compared to that of existing instruments.
Clodronate and pamidronate presented anti-nociceptive dose-responses, comparing favourably to aspirin and morphine, and the central and peripheral analgesia did not appear to be mediated through opioid receptors [ 46].
We recommend the use of more doses in toxicity tests, together with the benchmark approach as an appropriate and more accurate method for analyzing dose-response data compared to the NOAEL approach.
There was evidence of a dose-response effect: compared to subjects living in homes with no guns, the relative risk was 3.4 (95% CI=1.5 7.6) among subjects with one gun and 3.9 (95% CI=2.0 7.8) among subjects with multiple guns in the home.
In the dose-response analysis, compared with high dose rosiglitazone, low dose rosiglitazone was not associated with a significantly lower risk of the composite outcome (adjusted hazard ratio 0.94, 0.83 to 1.07), whereas both high dose pioglitazone (0.76, 0.66 to 0.88) and low dose pioglitazone (0.83, 0.70 to 0.97) were.
The discussion of propofol should be re-focused and expanded a little – this is now widely considered suitable for induction in pregnancy, and the main issues are the dose-response curve compared with thiopentone and the neonatal outcome, rather than uterine relaxation.
There was insufficient data to determine a dose-response effect comparing 1 ug versus 2 ug dosing.
Also problematic for an adequate interpretation, most dose-response or comparative studies compared continuous (not interval) high intensity endurance protocols that did not reach intensities (far) above the aerobic threshold [ 38].
Data are expressed as mean ± SEM; Animal characteristics and CS activity were compared using a 1 way ANOVA and the dose-response curves were compared performed by a 2-way ANOVA for repeated measures followed by Student-Newman-Keuls post-ANOVA tests (Statistica 7.1 software, StatSoft France, 2005).
Dose-response curves were compared by repeated-measurements ANOVA.
On the contrary, DBA mice raised by an AKR mother showed a downward shift in the dose-response curve as compared to mice raised by a C3H mother (mother effect F 1,17) = 4.6 p<0.05, dose*mother F 3,51) = 0.45 p = ns).
