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Intracellular calcium increased by Pb2+ treatment in a dose-dependent way (Fig. 1B).
In addition, exposure to SiNPs led to apoptosis in a dose-dependent way as indicated by gradually increased Bax (Fig. 3f).
The findings indicate that DHEAS changes the sleep EEG in a dose-dependent way, possibly through a modulation of GABA- and glutamate-induced currents.
Results: Recombinant human erythropoietin evoked reproducible contractions on the vessel rings in a dose-dependent way, which were marked significantly more on veins than on arteries.
The influence of the COX inhibitor, indomethacin, and the glucocorticoid, dexamethasone, which leads to inhibition of PLA2, was expressed in a dose-dependent way.
Concerning the transition temperatures, Fig. 2a shows that Tm decreased in a dose-dependent way for all three fatty acids, suggesting that these molecules tend to fluidify the DPPC membrane.
The results show an increase in intracellular Ca2+ concentration of transfected CHO cells (Fig. 1D) and in RBC (Fig. 1B), which also happens at higher Pb2+ concentrations in a dose-dependent way (Fig. 1F).
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In Fig. 4, we show that maintaining PEG in the culture medium after removing virus inoculum increased HBV infection in a dose dependent way (Fig. 4B).
AR induced by A23187 was indeed inhibited in a dose dependent way by KH7 (Fig. S1D).
Biofilm biomass quantification indicates that DNase I reduces biofilm formation in a dose dependent way (Fig. 3A).
These findings show that, in a dose dependent way, prophylactically administered CR6261 confers protection against lethal H5N1 challenge, prevents morbidity and viral dissemination and reduces pulmonary pathology.
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