Sentence examples for dose was interrupted from inspiring English sources

The sunitinib dose was interrupted in 25 patients and reduced in 12 patients across all cohorts.

The third patient experienced increased blood pressure (grade 2) which was not related to study drug, but possibly related to MPT; this patient's fourth sotatercept dose was interrupted due to haemoglobin levels of >130 g/l.

The capecitabine dose was interrupted or modified in spite of observed toxicity.

For patients with grade ≥3 venous thrombosis or embolism, the dose was interrupted and anticoagulation therapy was started.

The axitinib dose was interrupted in patients with grade 4 axitinib-related adverse events, two readings of systolic BP >160 mm Hg or diastolic BP >105 mm Hg, or ⩾2 g protein per 24 h, and resumed at one lower dose level when adverse events improved to grade ⩽2, BP decreased to <150/100 mm Hg, or<2 g protein per 24 h was present.

Toxicities associated with olaparib monotherapy were managed by dose interruption; in the event of a toxicity recurring after dose interruption, or if olaparib dosing was interrupted owing to a grade ≥3 adverse event (AE), dose reduction to 200 mg bid (and then, if necessary, to 100 mg bid) was considered or required, respectively.

Axitinib dosing was interrupted on day 10 of each cycle for 7 days.

Sorafenib dosing was interrupted during the delay in administering the chemotherapeutic agents, and then resumed at full dose when the next cycle of paclitaxel and carboplatin was given.

Crizotinib treatment was temporarily discontinued in 10 patients for up to 42 days; in some patients, dosing was interrupted repeatedly due to drainage procedures.

Sunitinib dosing was interrupted in 52% of patients for a median of 10 days, while capecitabine treatment was interrupted in 46% of patients for a median of 7 days.

Sorafenib dosing was interrupted for patients developing grade 3 toxicities, supportive measures were instituted, and sorafenib was reintroduced at one dose level reduction when the toxicity had improved to grade 1 or less.