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All doses were well tolerated, and no maximum tolerated dose was identified.
Moreover, the maximum tolerated dose was identified on a weekly schedule 20-300 mg/m).
No dose limiting toxicities (DLTs) or maximum tolerated dose was identified.
In addition, a significant association between HRV and antipsychotic drug dose was identified by multiple regression analysis.
Adverse events were similar to standard of care, and no maximum tolerated MM-111 dose was identified.
Planned etoposide dose was identified as a significant predictor of cycle 1 FN; however, very few patients received this agent.
Similar(48)
However, no bleeding events related to heparin dose were identified.
Several clusters of coregulated genes whose responses varied with DNA damaging agent dose were identified.
Ideally, dose-finding studies test progressively lower doses until an inactive dose is identified, thereby establishing a minimum floor.
The dose of oral cyclophosphamide at the time point of infection as well as the cumulative oral cyclophosphamide dose were identified as risk factors [ 84].
If one then considers the risk that a biologically maximally effective dose is identified because no responses are seen at a higher dose level, it becomes apparent that this can happen not infrequently.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com