Sentence examples for dose was first from inspiring English sources

If the score was greater than 17, a sign of insufficient sedation, the sufentanil dose was first raised; after 1 h, if the score was still greater than 17, a hypnotic, midazolam, or ketamine dose, depending on the physician's choice, had to be raised.

As in total analgesic dose prediction, the numeric value of PCA analgesic dose was first discretized into three symbolic values: "low," "medium," and "high".

The 18 mg/kg dose was first published to our knowledge in the paper by David M. Treiman et al[ 19].

This sub-critical dose was first reported by Zeng et al. (2006) looking at chromosomal inversions in cells taken from mice exposed to various X-ray doses.

The relationship between patient outcome and treatment dose was first introduced in a landmark study where patients randomised to post-dilution continuous veno-venous haemofiltration (CVVH) at a dose of 35 ml/kg/hour or above had improved survival compared with those randomised to 20 ml/kg/hour [ 4].

The term 'metronomic dosing' was first used by Hanahan et al (2000).

The efficiency of these two inhibitors to block the enzymatic activity of MMPs at different doses was first confirmed using recombinant MMPs.

In Jehle 2005 [ 17] (n = 10), after achieving IGF-1 normalisation, the interval between dosing was first doubled (dose every other day) and then, if IGF-1 normalisation was retained, doubled again.

Single-agent carmofur was administered as 3-week cycles, where carmofur 300 mg m−2, divided in three daily doses, was first given orally for 14 days, followed by 1 week of rest.

We also performed analysis beginning from 2000 when specific doses were first asked (Table 6).

39 In the extension, doses were first up-titrated to a maximum of 80 mg three times daily at week 6 in a masked fashion while the 80 mg group had sham titration.