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Increasingly, hemodialysis machines incorporate devices that measure ionic dialysance, allowing the dialysis dose to be determined noninvasively in real time and in each session.
Gurney (1996) argues for the introduction of a 'prime' fixed dose to be determined for each drug.
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The prefixed schedules used by those studies, however, did not allow the adapted doses to be determined.
The effective dose or range of doses needs to be determined.
Figure 2 Series of PET whole-body images from 4 to 356 min after injection of florbetapir F 18. Cumulated activities in each organ were determined for individual subjects to allow subject-specific dose estimates to be determined.
Whether these side effects could be mitigated at a lower dose remains to be determined.
For all types of toxicology tests, the best measures of nanoparticle dose need to be determined.
This may also allow a more scientific definition of "rapid dose escalation" to be determined.
If inositol supplementation is indeed effective in preventing GDM, the most appropriate dose needs to be determined.
As a prerequisite, a sensitive IL-1 dose had to be determined allowing observation of minor changes in IκBα levels and IKKβ phosphorylation.
Dosing regimens for subgroups such as highly infected patient groups, incremental benefits of drug combinations, double dosing and optimal interval between doses have to be determined to inform control programmes for urinary schistosomiasis.
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