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Some studies have shown that using the genetic test might allow the proper dose to be achieved more quickly.
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Such courses may only last 48 hours or until the cultures are definitely negative and therefore early measurement of levels is preferable if a safe dosing regimen is to be achieved.
The second priority was to ensure that 50% of the parotid glands received a dose < 30 Gy (to be achieved in at least one gland).
In addition, a sufficient dose of flecainide has to be achieved with the potential of side effects as this drug has a relatively narrow therapeutic range.
Loading doses enable AUC MIC targets to be achieved rapidly [86].
A more efficient device would allow a lower dose to be administered to achieve an effective dose at the site of action but the swallowed dose would also be lower, and hence the systemic absorption.
Second, sufficient dosing must be achieved to stay within the therapeutic window.
The blood brain barrier (BBB) provides a major obstacle to chemotherapy since therapeutic doses cannot be achieved by traditional drug delivery without severe systemic cytotoxic effects.
A reduction of effective dose up to 70% can be achieved with minimal effects on lung quantitative results.
The reduction of cumulative dose to patient and staff can be achieved by reduction of fluoroscopy time due to the usage of CBCT guidance [28, 30].
This clearly indicates that metabolic stability suitable for a compound to be dosed in vivo may be achieved with this structural template.
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CEO of Professional Science Editing for Scientists @ prosciediting.com