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This paper highlights many of the controversial aspects of RRT management in these patients, including when to start, which modality is preferable, and what dose to apply.
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Light is dose dependent, inexpensive to apply, easily delivered, and does not interfere with cellular pathways, and thus has significant advantages over chemical systems.
In some instances, imaging results have helped to support the choice of a biologically active dose to be applied in later Phase II trials.
Since the maximal volume that can be nebulized during PIPAC is about 200 ml, the total dose to be applied has to be limited to about 10%% of a standard HIPEC dose.
The choice of the dose to be applied for the highest mutant rescue is often left to the breeder's experience with the specific plant material, its genetics, and its physiology.
Reflected UV-C doses ranging from 5,000 to 22,000-µWs/cm2 were applied; the time to apply the doses ranged from ∼5 to 45 minutes.
Who better to apply a dose of fatalism -- you got no choice, kid -- than someone who began cutting hair for a living in Sicily when he was 12 years old?
At the insistence of European political leaders, Greece's governing Socialists voted to apply another dose of growth-killing austerity to the country's nearly inert economy.
Participants were instructed to apply a dose once daily, preferably at bedtime.
d) To apply one dose of tetanus vaccine.
In order to apply this dose, intratracheal fluid administration of 16.0 ml/kg body weight was required.
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