Exact(33)
Aiming for a more modest and intermediate pH target with bicarbonate dose less than half of that predicted, or dose titrated based on pH severity, were some of the variable approaches adopted subsequently by investigators [4, 23].
Surprisingly, in our system a "sufficiently high dose" titrated to only 10 nM OHT applied for 48 hours for our lowest mCrem expressing clone, a dose 100 fold lower than our standard OHT dose and 5 fold lower than the dose used in a previous study [24].
metformin (dose titrated up over 4 weeks starting at 500 mg b.i.d).
No patients had their drug dose titrated and it was assumed that there was no vial wastage in drug usage.
Midazolam is administered by continuous intravenous infusion in critically ill neonates and the dose titrated according to the response.
A citrate solution is infused before the filter, being the citrate dose titrated to maintain ionized calcium levels in the extracorporeal circuit below 0.3 0.4 mmol/l.
Similar(27)
The model was first characterized by dose titrating ALN and determining areal BMD of the distal femur (DFBMD) using ex vivo DXA.
27 However, individual dosing titrated to effect makes this population comparison between younger and older patients less clinically meaningful.
Careful initial opiate dose adjustment should be made in the setting of these interactions, patients monitored closely, and doses titrated accordingly.
Studies which reported these side effects used the drug for 8 weeks to doses titrated up to 3600 mg per day, unless severe adverse effects were developed.
Conventional weight-based dosing of GH (0·04 mg/kg/day) (n = 34) or GH dosing titrated to an IGF-I target of 0 SDS (IGF0T; n = 70) or an IGF-I target of +2 SDS (IGF2T; n = 68).
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