Sentence examples for dose strategy from inspiring English sources

Moreover, interindividual PK variability in the critically ill, and the consequent unpredictability of drug concentrations, suggests that an empirical fixed dose strategy is unlikely to be successful [14, 15].

A derivation is given on how to extract the recommended quadratic relation between dose and body mass, directly from the linear dose strategy that is currently applied in clinical practice.

The cost for the 3- dose strategy (dash-dotted line) would exceed that for the 2-dose strategy (dashed line) at all coverage rates modelled.

Based on previous research findings, pharmacokinetic data and patient outcomes; the single dose strategy is warranted.

The dose of the introduced LAI form will correspond to the equivalent of the used oral dose (strategy of choice).

Hence a reduction in the age of routine measles immunisation and possibly a two dose strategy should be considered.

For those who can do it without falling dead asleep, that is precisely the periodic low-dose strategy that seems to work best.

Among patients with estimated glomerular filtration rate below the median, those randomized to a high-dose strategy had improved symptoms compared with those randomized to a low-dose strategy.

In the comparison of the high-dose strategy with the low-dose strategy, there was a nonsignificant trend toward greater improvement in patients' global assessment of symptoms in the high-dose group (mean AUC, 4430±1401 vs. 4171±1436; P=0.06).

There was no significant difference between these groups in the mean change in the creatinine level (0.08±0.3 mg per deciliter [7.1±26.5 μmol per liter] with the high-dose strategy and 0.04±0.3 mg per deciliter [3.5±26.5 μmol per liter] with the low-dose strategy, P=0.21).

In our study, we compare two different methods of administration: single-dose or repeated-dose strategy which was most frequently applied over the years in our centre.