Sentence examples for dose selected from inspiring English sources
15 The interim analysis conducted at 24 weeks led to the eventual selection of DRV/r 600/100 mg twice daily as the dose selected for further clinical evaluation.
No immunogenicity impacting on the pharmacokinetics/pharmacodynamics of MEDI4736 has been reported at the 10 mg/kg every 2 weeks dose selected for further clinical development.
Similarly, no sign of tolerance was seen with 10-day repeated administration of JNJ at 30 mg/kg p.o. dose, selected based on acute dose-response study.
Treatment with 30 mg, the dose selected for the pivotal trials, was associated with a trend toward reduced 60-day mortality or readmission for cardiovascular or renal cause (hazard ratio, 0.55; 95% confidence interval, 0.28-1.04).
The dose selected, was 20 times higher than that of rosiglitazone on the basis of the pharmacokinetic profile of the compound, so as to have the sufficient exposure to show the pharmacological effect.
Our dose of GTN is considerably smaller than the dose chosen in experiments that administered GTN as an i.p. bolus injection [38, 39] but is 2.5 fold higher than the dose selected by Offenhauser et al. [31]in a study that failed to induce Fos expression.
The PTX/BVZ therapies and the dosing selected for this study were based on our previous pilot studies and other preclinical studies [22, 23].
Results from this proof-of-concept study were therefore consistent with the cell culture studies and provided the basis for the doses selected in the phase II study.
The doses selected here ensured a reasonable discrimination of receptor activation at physiological concentrations.
The drug doses selected have previously been shown to influence behavior in mice (21,31).
Each compound was profiled across eight doses selected to sufficiently cover response dynamics.
