Sentence examples for dose safety from inspiring English sources
According to the dose safety level upto 2000 mg/kg two doses of BR extract, i.e. 250 and 500 mg/kg were selected for in-vivo antidiabetic study.
In this design, patient enrollment does not need to stop when transitioning from the evaluation of the dose safety and tolerability to the assessment of its efficacy.
Here, we compared the long-term fingolimod (0.5 mg dose) safety data in the LONGTERMS study (up to data cut-off), with shorter-term (1 2 years) safety data pooled from the randomized controlled trials.
We aimed to determine the recommended phase 2 dose, safety, pharmacokinetics, and preliminary activity of tucatinib in combination with capecitabine or trastuzumab in patients with HER2-positive breast cancer with or without brain metastases.
We now report the use of dihydrexidine DAR-01000), the first full D1 agonist, in a pilot study assessing single low dose safety and tolerability in patients with schizophrenia.
Secondary objectives included reactogenicity, anti-HBs antibody response and anti-CS response, and the 1 year post last dose safety and immunogenicity follow up.
Descriptive statistics were provided by initial planned dose (safety- and efficacy-evaluable patients) and overall dose level (safety only).
This was a multi-center, open-label, repeat-dose safety study in adults with episodic migraine with and without aura.
RG7716 is a novel bispecific antibody that simultaneously binds vascular endothelial growth factor (VEGF) and another key angiogenic factor, angiopoietin 2. A phase I study of intravitreal RG7716 was conducted to evaluate single-dose and multiple-dose safety in patients with neovascular age-related macular degeneration (AMD).
However, questions remain about their efficacy, dosing, safety, and how these approaches compare with other therapies.
In a recent review of expanded access proposals reviewed by the FDA, the agency recommended changes to dosing, safety monitoring or informed consent in 11 percent of cases.
