Scientists do not know enough about dose, route of exposure, incubation period, genetic susceptibility and scale of the species barrier between cattle and humans.
Transplanted cell survival and engraftment is determined by multiple parameters including animal model, cell type, dose, route of administration and treatment duration.
Ideally, BCMAs help confirm the five "rights" of medication administration: right patient, drug, dose, route, and time.
The optimum dose, route and timing of administration remain to be determined.
When combined with morphine, caffeine can augment, inhibit or have no effect depending on the dose, route of administration, nociceptive test, and species.
Nonetheless, despite the effectiveness of delivering a bronchodilator via the metered dose route [3, 4], nebulized salbutamol is still very much preferred because of its convenience [5].
The vaccine, dose, route and schedules selected were based on experience with numerous other malaria vaccine trials in nonhuman primates [26], [27], [28].
Both mouse studies employed the same mouse strain (B6SJL-TgN SOD1-G93A 1Gur) and lithium salt, formulation, dose, route, and frequency.
The dose, route and timing of these treatments were based on reported half-life for these agents, prior publications and preliminary experiments demonstrating efficacy [6], [21].
Documented details include form, dose, route, frequency, and duration of drug administration.
We assessed which evidence-based elements, such as therapy dose, route, and timing, were evaluated.
