Sentence examples for dose response at from inspiring English sources

In contrast there was a trend toward blunting of the skeletal muscle myosin dose response at high PO2 (Figure 1B); the Ki for inhibition was 3240 and 138 nM [NO] at 152 and 15 mmHg PO2, respectively (p = 0.03).This suggests that at physiologic oxygen concentrations the response of myosin to nitrogen oxides is already maximized.

The accumulation of Gaucher cells and GC in 9 V/null mice provided the opportunity to evaluate dose response at a tissue level and also to conduct comparative studies of the two GCases at three different doses; the dose range was 12-fold (5 60 U/kg/wk).

In the low density tanks the tadpoles with the lowest growth rate were those exposed to the highest virus dose (Figure 1D) indicating a dose response at this density: there were significant differences between Dose 3 and control, and Dose 2 and control (F = 14.64, df  = 1, p<0.001 and F = 6.07, df  = 1, p = 0.0141, respectively).

Thus, there is essentially no dose response at clinically achievable levels.

Similarly, the objective function was penalized if the pERK dose response at the relevant time points was not qualitatively biphasic.

The BPI data also showed a significant dose response at week 8 for the Pain Severity Index (P = 0.040).

The obtained transcriptional dose responses at 4 h after irradiation are presented in Fig. 1 and Fig. 2 relative to the non-irradiated control.

Indeed, numerous reports confirmed the lack of linearity in radiation dose responses at low doses for such end points as micronuclei (Słonina et al. 2006), chromosomal aberrations (Nasonova et al. 2006), cellular clonogenic survival (Marples and Joiner 1993) and others.

We also tested E2, dieldrin, NP, and BPA dopamine efflux dose responses at 5 min to examine the different flux states caused by these compounds at optimally active response times (for enhancement or inhibition) for each.

While this model may be appropriate for risk predictions at high doses, the shape of the dose response curve at low doses is not well understood.

Future feeding studies with YP should consider dose response designs at YP feeding levels higher than those used in past studies, as well as report BW and BW change to allow YP response on animal energetics to be assessed.