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For the types of exposure used in the present investigation Leq alone is not an adequate descriptor of the noise dose, relating to the sleep disturbances observed.
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The conclusions drawn were that the therapeutic effect of IFN is not dose related, nor related to treatment duration.
Overall, PX-866-related gastrointestinal AEs were dose related.
The effect of prucalopride on stool frequency and constipation-related symptoms is clearly dose related.
Many opioid-related adverse events, such as respiratory depression, are dose related.
Hyponatraemia occurred more frequently in patients on oxcarbazepine and is dose related.
All participants reported a dose related headache (median peak = 2.5, range 0-3).
The most common irAEs include dermatitis, enterocolitis, and hypophysitis and are dose related [3].
Additional dose related to MV image guidance is evaluated at 1 to 3cGy per fraction.
Oral E2 and ethinyl estradiol (EE) generated dose related uterine growth and important hepatic estrogenic effects.
Increase in Cmax was observed which might help in dose reduction along with reduction in dose related side effects.
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