The endoscopic cure rate was dose-related for the ITT population at 68.8%, 77.4%, and 89.9% for micafungin doses 50, 100, and 150 mg, respectively.
For cells from xenografts of the NCI-H69 human small cell lung cancer line, the response to radiation was dose-related for both assays, but the curve for clonogenic assay was about twice as steep as that for isotope uptake.
It has been suggested that when taking into consideration particle number or surface area, the pulmonary dose of toxic material related to PM2.5 may be much larger than the dose related to PM10-2.5 PM10-2.5 that reason alone, comparison on a mass basis may be less informathis [ 15].
Specifically, the oncogenic study demonstrated dose related effects for single one-hour exposure of VCM at high levels, i.e., 5,000 and 50,000 ppm.
No statistically significant difference was found between exposed and non-exposed periods, nor was there any dose related trend for different individuals when grouped into different exposure groups.
For all drugs adverse events are likely to be dose related, with higher event rates at higher doses.
Mage criticizes us for not subtracting preapplication urine values in our assessment of systemic dose related to on-study applications.
The number of caregivers reporting concerns about their child's falling asleep at night appeared to be dose related: 5 (33.3%) for subjects receiving MTS 15 mg, 15 (37.5%) for subjects receiving MTS 20 mg, and 38 (34.8%) for subjects receiving MTS 30 mg.
Since many adverse events are dose related, appropriate dosing for analgesic medications in this sensitive population is a particularly important clinical concern.
In many cases this association is dose related, adding further evidence for an etiological role for the metalloid in this important human cancer.
A dose related association was observed for hip fractures as well as for any fracture in both men and women (table 5).
