Stratification of trials by CKD stage, weekly vitamin D dose, proportion of diabetic subjects and vitamin D compound displayed similar results.
Stratification of trials by CKD stage, average weekly standardized vitamin D dose, proportion of diabetic subjects enrolled and vitamin D analog showed similar findings.
We will also provide descriptive statistics on the changes in concomitant diabetes medications during the observational period (proportion of subjects adding therapy or increasing dose of preexisting therapy; proportion stopping therapy or decreasing dose; proportion not changing therapy).
However in our experimental conditions, we did not observe this better effect when both factors were added in the same implant at the same amount; perhaps because the dose, proportions and the timing for their administration.
Secondary endpoints were total number of ciprofloxacin doses, proportion of inappropriate IV ciprofloxacin doses, cost of therapy between phases, and estimated cost avoidance with the intervention.
Change in HSDS per GH mg/kg/day dose (ΔHSDS/GH dose ratio) and proportion of IGF-I levels above +2 SDS at the end of 2 years.
Clinical trials have shown conflicting results for the efficacy of omega-3 polyunsaturated fatty acids in IgA nephropathy, which may relate to varying doses, proportions of eicosapentaenoic acid and docosahexaenoic acid, duration of therapy, and sample size of the study populations.
In their study of men, Strasak and colleagues observed that incident cancers occurred in dose-proportion to baseline GGT levels (P for GGT log-unit increase < 0.0001; P for trend < 0.0001).
Similarly, fatal CVD events among women followed a dose-proportion relationship that became significant at GGT levels above 18 U/L with an incremental mortality risk of 35%; at GGT levels between 18 and 26 U/L, increased mortality risk was measured at 46%, and at levels above 36 U/L, it was shown to be 51%.
Applying the new characterization of SIAs to ensure consistency with the historic reported zero-dose proportions among non-polio AFP (NPAFP) cases over time, rather than estimates based on expert judgment, led to some adjustments of generic and situation-specific model inputs in order to produce more realistic historic poliomyelitis incidence (see Additional file 1, Table 1).
In standard dosing analyses, at the lower doses, the proportion of patients improves with increasing dose, but as the dose increases to some higher level, further improvement is attenuated and approaches a threshold (see Figure 2).
