Your English writing platform
Discover LudwigExact(3)
Subjects participated in one of seven dose panels.
Four apixaban dose panels were tested: 2.5, 5, 10, and 25 mg twice daily.
Availability of a quantitative prediction model during dose escalation that is updated with emerging clinical data from early dose panels may give increased confidence in predicting pharmacology and safety.
Similar(57)
Crosslinking with DTME was less efficient, as evidenced by the relatively high levels of monomeric E-cadherin remaining at the 1.0 mM dose (panel c, compare lanes 1 and 6).
Escalation to the next dose panel occurred only if safety data through day 3 for six subjects in the ongoing dose panel were considered acceptable by the investigator and sponsor.
Twenty-seven inpatients with major depression were admitted subsequently to a clinical trial with the CRH1-receptor-antagonist R121919 administered in two different dose escalation panels.
Figure 1 depicts the kinetics of cefepime concentrations in the plasma versus time at the first-dose (left panel) and at steady-state (right panel), respectively.
Treatment regimen characteristics associated with shorter persistence include efficacy, tolerability profile, and regimen complexity (e.g., higher pill burden and dosing frequency; Panel on Antiretroviral Guidelines for Adults and Adolescents, 2009; Elzi et al., 2010).
In panel A, we sketch the linear model of dose response, whereas panel B shows that this model fits well to the trial data.
Based on the findings, the 450 Gy was the best possible dose for AL8/78-DGRH1 AL8/78-DGRH1panel.
The effect of liraglutide on insulin secretion is illustrated in Figure 5, in terms of model predicted insulin secretion for trial 1 at all dose levels (left panel).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com