The delineation of the target volume, i.e. the volume which should be irradiated with a therapeutic dose of irradiation, is of utmost importance in radiotherapy.
The inability of 200 Gy of gamma-irradiation to decrease H-thymidine incorporation of melanoma cells to less than 5% of that seen in the corresponding non-irradiated controls could be the result of using too low a dose of irradiation, although the dose chosen is at the upper limit of what has been used in other studies [ 24- 29].
The total dose of irradiation was up to 6.24 MGy.
Crystallinity increases with increasing dose of irradiation in both vacuum and oxygen, with level of increase is greater in oxygen.
Degradation nature was tested by studying the changes in mechanical and thermal properties with rate and total dose of irradiation.
The accepted threshold dose of irradiation that will cause radiation nephropathy is a total dose of 28 Gy, fractionated in 5 weeks or less [8].
After irradiation, the glass density increased and the SAXS intensity decreased, indicating a compositional homogenization process in the samples subject to a higher dose of irradiation.
The present study was designed to investigate the protective effect of rutin and low dose of irradiation (LDR) on cisplatin-induced nephrotoxicity in rats.
According to the excessive response model survived tumor cells may obtain higher capability to deal with additional ROS-generating insults and higher dose of irradiation, which makes them harder to be killed by the immune system.
The results showed that the initial toluene degradation rate increased (from 0.0062 up to 0.0567 μmol/min) with raising initial toluene concentration (50 400 ppm), while too high dose of irradiation (about 50 mW/cm2) reduced photocatalytic toluene degradation rate.
In the case of combination treatment, drug or vehicle was given for 2d prior to the first dose of irradiation.
