Sentence examples for dose may lead from inspiring English sources

Conversely, a large dose may lead to very small amounts of propranolol in the blood.

Recently, much experimental work has focused on the mechanisms by which site-specific toxicity arising from chronic administration at the maximum tolerated dose may lead to carcinogenicity.

Exposure of the heart to even a low radiation dose may lead to an increased risk.

If infection does occur, the postexposure vaccine dose may lead to milder clinical manifestations, lower complication rates, and shorter duration of virus shedding (15 ).

However, it is possible that mismatched timing of meal phosphate intake and binder dose may lead to an increased number of phosphate binders being taken than are required.

Because poor metabolisers are unable to metabolise CYP2D6 substrates, a drug administered at normal dose may lead to high or toxic levels of the drug [ 11, 12].

This alkali element and its salt, at its higher doses, may lead to various side effects or has several toxic effects after prolonged therapeutic use.

The impetus for this study was our clinical experience that, in some TN patients showing poor responses to BTX-A, repeated dosing may lead to better pain relief.

Poor knowledge and underestimation of radiation doses may lead to ionising imaging examinations being prescribed unnecessarily, resulting in an increased risk for patients.

Conclusion Baclofen, prescribed in high doses, may lead to severe intoxications: self-poisonings frequently require endotracheal intubation and are associated with an increased risk of death.

These contradictory results are partly explained by dose-dependent effects of BDNF with low doses causing hyperalgesia, whereas higher doses may lead to analgesia, an effect that might be induced by the activation of different intracellular pathways [13].