Sentence examples for dose local from inspiring English sources

Accidental intravenous injections of high dose local anesthetics have been reported to cause mild (such as lightheadedness or metallic taste) to severe (such as cardiac arrhythmia or epileptic seizures) adverse effects [41].

In this article the study designs currently accepted for the nonclinical safety testing of new vaccines are described for single dose, local tolerance, repeat dose toxicity and safety pharmacology studies; these studies together form the basis of a typical nonclinical safety evaluation dossier.

A low dose local anaesthetic and opioid solution (bupivacaine 0.1% with fentanyl 2 μg/ml) was used for epidural analgesia.

26 The use of low dose local anaesthetic and opioid solutions for epidural analgesia was not an exclusion criterion.

Our retrospective analysis revealed that intra-articular injection of high dose local anesthetics provided similar analgesic efficacy as FNB and might be associated with early ambulation.

Low dose local anaesthetic and opioid solutions containing fentanyl do not significantly prolong gastric emptying, 27 28 unless the amount of fentanyl administered exceeds 100 μg.

In the present case, general, neuraxial, and large-dose local anesthesia posed potential risks of serious complications.

To evaluate the effect of a single-dose local administration of PTH on bone healing in rat calvarial bone defects by means of micro-computed tomography, histological and histomorphometric analysis.

Low-dose local ET is as effective as systemic treatment.

This apparently paradoxical effect of TNF- α on tumour may reflect the difference in chronic synthesis and acute high-dose local administration.

This suggests that, under given parameter values, even multiple, high-dose local administration of the virus to accessible tumors (a usual clinical practice) will be ineffective.