Sentence examples for dose level increased from inspiring English sources

As dose level increased, the rhizome size decreased.

Combining the data from all three studies, while the mean AUC at each dose level increased with dose, it appeared that the association between AUC and dose is nonlinear (R=0.34).

At very low doses levels there is no evidence of toxicity, but as the dose level increases the prevalence and severity of toxic effects increase.

In the phase I study, cohorts of two patients received a stepwise dose level increase to achieve the maximum tolerated dose (MTD), at which a total of six patients were studied.

Standard phase I designs assume that both the probabilities of toxicity and efficacy of a new drug increase as dose level increases.

In this simulation study, we originally find that the ETL decreases monotonically from about 30% to 0% as the number of dose levels increase from 3 to infinity, which will correct the inaccuracy in the common belief among phase I trial investigators.

In Figure 9B, results are shown from simulations with the same initial conditions as in panel A. The threshold dose duration required to restore health is predicted to decrease as the probiotic dose level is increased.

Inclusion of a higher dose level only increased the precision of slope estimates (data not shown).

If no additional patients had a DLT until the end of week 10, then the dose level was increased.

In the case of the 30 mg/kg QD dose, reticulocyte levels increased by ∼4-fold, resulting in ∼30% increase in RBC levels (plateau) and >4 g/dL increase in HGB levels (plateau), as shown in Figure 6.

Increasing dose levels showed increasing hematologic toxicity, but no patient demonstrated neutropenic fever, infection, or hemorrhage.