Sentence examples for dose is difficult from inspiring English sources

Because a tumoricidal dose is difficult to achieve using external beam radiotherapy without exceeding the spinal cord tolerance, we developed intraoperative applicators to deliver additional dose to the dura.

Finding the optimum biological dose is difficult.

Such a small change at this high dose is difficult to interpret.

A large dose of contrast agent saturates the image, while delivery of a low dose is difficult on a consistent basis.

The incubation period from exposure to onset of the disease may be very long, and therefore the exposure dose is difficult to define.

Despite the acknowledged success of physiotherapy rehabilitation combined with BoNT-A injections, relative effectiveness of the specific components of physiotherapy rehabilitation, including intensity and dose, is difficult to interpret because it is often poorly described [ 14, 15, 17, 25].

The fact that several biological parameters influence the haematological response may explain why strong correlations with absorbed bone marrow dose are difficult to find.

The average weight of each sample was 10 g to be consumed over a period of few days ranging from 3 to 21 days and hence daily dose was difficult to calculate.

Clinical symptoms are diagnosed, even with low dosing regimens, so that safe dosing is difficult and use is associated with a high expenditure in terms of the need for control visits [4].

Translating these data into monthly or annual worker doses is difficult.

The elevated saquinavir concentration may have arisen as a consequence of deranged hepatic function since saquinavir is metabolized in the liver and adequate dosing is difficult.