Sentence examples for dose hazard from inspiring English sources

Health risk assessment of As, Pb, Fe, Cd, Ni and Zn based on the average daily dose, hazard quotient and cancer risk was also determined.

Olmesartan initiators had a small but significantly increased risk of developing diabetes after adjusting for baseline characteristics and mean daily dose (hazard ratio [HR], 1.07; 95% confidence interval [CI], 1.03-1.12).

In the subanalysis of accumulated number of TNF-α inhibitor doses, the risk of serious infections was significantly increased in patients receiving a single dose (hazard ratio 1.64, 95% confidence interval 1.06 to 2.53) and decreased thereafter in those receiving two or three doses (1.18, 0.79 to 1.78) and four doses or more (1.06, 0.66 to 1.69, fig 2).

Results: We examined how dose-dependent responses of zebrafish embryos exposed to flusilazole can be extrapolated, using pathway point of departure data and reverse toxicokinetics, to obtain human oral dose hazard values that are similar to published mammalian chronic toxicity values for the chemical.

Dearnaley et al. [ 38] conducted a pilot for a phase III trial randomising 64 Gy versus 74 Gy and reported 5-year biochemical control rates of 59% (standard dose) and 71% (escalated dose) (hazard ratio 0.64, 95% CI 0.38 1.10, P = 0.10) with acceptable acute and late toxicity [ 27].

Other variables that were associated with cessation rate were current use of a 20 mg daily dose (Hazard Ratio = 1.68, 95% CI 0.79 to 3.56) and use of triple DMARD therapy at the time of leflunomide initiation (Hazard Ratio = 2.2, 95% CI 0.97 to 5.2), but these did not reach statistical significance (P = 0.18 and 0.057 respectively).

In dietary risk assessments provided to regulatory agencies, it is routinely demonstrated that the potential human dietary intake of various introduced proteins is orders of magnitude below the highest dosages administered to rodents in acute high-dose hazard toxicity studies that produced no adverse effects (Betz et al., 2000; Hammond & Cockburn, 2008).

In the combined 100-mg daily dose, the hazard ratio (placebo:azimilide) was 2.35 (P =.023).

EADI for Heptachlor and Aldrin in Tilapia zilli were higher than their recommended reference dose while Hazard Quotient (HQ) values were above one (1) suggesting that the potential health risks associated with intake of Heptachlor and Aldrin, through the consumption of Tilapia zilli was high.

In analyses of dose, adjusted hazard ratios increased significantly with dose for selective serotonin reuptake inhibitors and other antidepressants (both P<0.001) and also tended to increase with dose for tricyclic antidepressants (P=0.013) (table 3).

These subsections are followed by one on exposure assessment, and a final section which includes analyses of dose-response (hazard) assessment and risk characterization.