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The variables analyzed in order to determine their influence on circuit life were catheter and venous access used, blood flow rates, heparin dose, filter surface area, filtration fraction, ultrafiltration rate, and total effluent flow rate (ultrafiltration plus dialysis).
As this modality may be more caregiver-friendly in terms of implementation, we conducted a randomized controlled trial in ICU patients requiring CRRT to determine whether a balanced predilution replacement fluid with citrate was more effective than heparin in terms of delivered renal replacement dose, filter lifespan, safety profile and patient survival.
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The dose filtering scheme has been integrated in a new program for frame alignment.
The effects of blocking reagent dose, filtering, and background corrections methodologies were investigated.
3) The dose filtering was tested on the same data that was used to derive the critical dose curve.
Is the dose filtering optional and (in light of the previous comment) are the values hard-wired?
The authors should justify its use here, showing or explaining how it still applies to the Ne values measured from SNRs and the FSC. 3) The dose filtering was tested on the same data that was used to derive the critical dose curve.
Fresh urine (1 mL) was collected 60 min after dosing, filtered through a 0.22 μm Millipore filter, and subjected to HPLC analysis.
But also the treatment dose and filter lifespan are variables that interfere in the results.
It is unsurprising that a positive correlation between heparin dose and filter life exists.
However, Leitner and colleagues also observed a 20to25%5% loss of initial anidulafungin dose by filter adsorption [ 3].
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