Sentence examples for dose escalated from from inspiring English sources

Among the 137 patients who dose escalated from 50 mg to 100 mg through week 160 (figure 1), within 12 weeks following dose escalation, ACR20 and ACR50 response rates increased and were generally maintained over the subsequent 88 weeks.

Everolimus was dose escalated from 15 to 30 mg and administered with paclitaxel 80 mg m−2 on days 1, 8, and 15 every 28 days.

As oral bioavailability is high (70 100%), nolatrexed was administered orally, 6 hourly for 10 days, at 3-week intervals, and dose escalated from 80 to 572 mg m−2day−1in 23 patients.

Interestingly, most patients (11/19, 58%) in cohort 2b had their erlotinib dose escalated from 75 to 100 mg day−1 during cycles 2 6, indicating that the higher dose could be reasonably well tolerated when used in combination with chemotherapy, after an initial lower dose.

Another experience from Hata et al. included 21 patients treated with doses escalated from 50 GyE to 60 GyE in 10 fractions, as in the previously described study [ 31].

In a phase I trial by ECOG, seven patients with LAPC were treated with radiation (59.4 Gy) and infusional 5FU with Gem doses escalated from 50 to 100 mg m−2 per week.

Fifty-three patients were treated at doses escalating from 7 to 259 mg/m.

Fifty-three patients were enrolled in the study between January 2008 and January 2010 and treated at doses escalating from 7 to 259 mg/m.

26 Another phase I study evaluating the same duo of drugs evaluated 38 previously untreated STS and breast cancer patients with a dose of 60 mg/m of doxorubicin and trabectedin in doses escalating from 600 μg/m to 800 μg/m which was the MTD due to febrile neutropenia.

Of note, afatinib-treated patients were permitted to dose-escalate from the initial 40 mg dose to 50 mg/day after the first 21-day treatment cycle if no drug-related AEs higher than grade 1 were experienced, while dose reductions in 10 mg decrements to a minimum final dose of 20 mg were recommended for patients experiencing drug-related grade 3 or selected prolonged grade 2 AEs [ 66, 67].

Cyclophosphamide dose was fixed at 500 mg m−2 and losoxantrone dose was escalated from a starting dose of 30 mg m−2 through 40, 45 and 50 mg m−2.