Dose errors were still prevalent with CPOE, however, as a result of physicians choosing the wrong drug template, selecting from multiple options, or as a consequence of constructing their own drug prescriptions using pull down menus.
In addition, two cases of ten-fold dose errors were intercepted with the prescription of 1, 830 mg of etoposide instead of 183 mg and 1, 830 mg of cisplatin instead of 183 mg.
The cumulated dose errors were then calculated and defined by the differences between the LM reference cumulated dose (from the first expert) and each of the estimated LM cumulated doses (from the DIR, from the rigid registration methods and from the second expert).
Considering all the LMs, the methods corresponding to the lowest cumulated dose errors were the "FFD with MI on filtered CTs" and the "demons with MI on filtered CTs," with corresponding accuracy (and precision) of: 0.85 Gy (and 0.93 Gy) and 0.88 Gy (and 0.95 Gy), respectively.
Dosing errors were the most common error type.
Drug dosing errors are common in renal-impaired patients.
Medication dosing errors were common; under-dosage for ampicillin, gentamicin and cloxacillin was found in 44.0%, 37.9% and 50% of cases, respectively, while over-dosage was found in 20.0%, 24.2% and 19.9%, respectively.
It is possible that some students felt that such a dosing error is unlikely to be clinically significant, though we would note a case report of an 800 mg dose administered to an infant following a circumcision resulting in hepatotoxicity [ 17], and even underdosing holds the potential for clinical significance.
Thereafter, the nurse was interviewed and a dosing error was identified: she had mistakenly given the patient 1 mg of phenylephrine (1 mL) instead of 100 mcg (1 mL of the standard dilution, 1 mg in 10 mL).
