Sentence examples for dose enrolment from inspiring English sources

The univariable and multivariable risk factors identified in those studies are shown in Supplemental Tables 1 and 2. Clinical covariates in the current study were included based on the previous analyses as follows: (lumefantrine or amodiaquine dose, enrolment parasitemia, age category, and ASAQ fixed or co-blistered versus loose formulation (Table 1).

Factors influencing the selection of the IVIG dose before enrolment were not standardized.

If two or more patients presented with DLT at a dose level, enrolment of patients to that dose level was discontinued and the immediately preceding dose level was considered the MTD.

The dose at enrolment began at 0. 6 ml (6 mg) daily until the 2 week visit at which point the dose increased to 1. 5 ml (15 mg) given as a daily dose until the 5 week visit.

These six patients, whose mean predniso(lo ne dose at enrolment was 0.51 mg/kg (SD 0.32), were all responders to 1 month of anakinra treatment and had already achieved ACRpedi 50 or 70 improvement at this stage.

We have reviewed characteristics of three alternative design options from an early (Phase 2) drug development perspective; enriched enrolment, dose titration and adaptive dosing.

The cumulative oral prednisolone dose received before enrolment (g) was calculated for each individual.

However, circulating parasites in all participants were cleared with atovaquone-proguanil treatment prior to the third vaccine dose, and therefore the enrolment parasite population itself was not placed under selection by vaccine-elicited immunity.

If three of three patients or at least four of six patients experienced the DLT, enrolment at this dose level was ceased, the dose level was determined as the MTD, and the preceding dose level was designated as the RD for the phase II study.

Thus, enrolment continued to dose level 2. Four patients were enrolled into the dose level 2 cohort (capecitabine 600 mg/m), as one patient was erroneously taking half of the prescribed dose of capecitabine (300 mg/m) and was replaced for DLT evaluation.

Doses were given at enrolment and repeated 4 weeks from baseline.