Exact(2)
As with the two Los Alamos criticality accidents involving the demon core, victims who were close enough to receive a lethal dose died, while those farther away recovered and survived.
These experiments (experiments 4 and 5) both revealed that the individuals exposed to a higher parasite spore dose died faster than those exposed to lower quantity of parasite spores or not exposed.
Similar(58)
According to the research, one in 32 patients whose treatment regimen on opioids was increased to very high doses died; they did not start on a high dosage.
Dr. Frieden cited one study that found one of every 32 patients started on opioid therapy whose treatment was increased to very high doses died of opioid-related causes.
Figure 3 shows that on the fifth day, all wild-type mice exposed to the high-dose died.
Mice receiving 100 mg/kg body weight of plumbagin died within 4 8 days, whereas those receiving 50 mg/kg body weight dosing died within 8 11 days.
Fig. 3 shows that all mice challenged with different protein doses died within 2 to 3 days, while the highest dose caused 80% mortality on day 1.
Pigeons infected with high doses died 7 12 days after infection and had massive parasite-induced liver necroses; those infected with lower doses had central nervous signs, which did not develop until 8 weeks after infection.
In addition, if one of the first 6 patients, receiving at least 70 80% of the planned doses died because of toxicity, the study would be discontinued, and depending on the reason of toxic death the protocol would be amended or permanently discontinued.
Nevertheless, untreated control rats, pair-fed at the same caloric intake as rats treated with lethal TCDD doses, die at much the same time as their TCDD-exposed partners [ 41].
1/12 (8.3%) low dose recipients and 6/12 (50%) high dose recipients died within 11 days after transfusion.
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