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Data was collected on film at 50,000× magnification and under low dose data collection conditions.
Also, a centralised dose data collection algorithm for therapeutic procedures would allow for improved analyses of dose-effect relationships for adverse events, including stochastic radiation sequelae.
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Images showing no systematic phase error due to charging are achievable under conditions of low-dose data collection.
The experimental procedures for sample preparation, TMA dosing, and data collection have been described in detail in our previous publication.
In this commentary, we discuss dose assessment and data collection guidelines to support both types of studies.
A Sr constancy source (Atlantic Research Co Model B-1 S/N 252) was used to insure proper response of the Capintec dose calibrator during data collection.
Because no investigational agents were administered and chemotherapy was given per standard dose and schedule, data collection was limited and safety reporting was not required for this phase of the trial.
This perhaps suggests that low-dose electron diffraction data collection is ultimately limited by radiation damage or the number of electrons per Bragg peak, in contrast to XFELs where radiation damage is circumvented, even at high-photon flux.
Toxicity-per-cycle data is given only for the first six cycles, in patients on the formal phase II trial, to avoid bias from dose reductions and differing data collection methods (Table 4-wrap>).
Diuretic dosing is a component of the data collection and dosage of diuretics in mg/kg/h will be calculated for each episode.
It is unlikely that a relative risk of this magnitude would be detectable in the present study after its statistical power, modest variations in dose rate and limitations of data collection are taken into account.
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