Dose conversion between rodents and humans followed the US Food and Drug Administration FDAA) guidance.
For this purpose, MCNPX flux to dose conversion factors reused.
Absorbed doses and dose equivalents were estimated from the spectra by applying fluence to dose conversion coefficients.
Thus, the estimate of the tissue or organ dose is the measured quantity multiplied by the absorbed dose conversion coefficient.
Cohorts that used tiered dose conversion tables trended towards having more stable peginesatide doses than did those cohorts that used a single dose conversion ratio.
An alternative explanation is that the initial peginesatide doses that resulted from tiered dose conversion tables were higher than those that resulted from a single dose conversion ratio.
Data were unavailable on over-the-counter purchases of high-dose aspirin and low-dose ibuprofen dosing schedules.
†Corticosteroid dose presented as prednisone-equivalent dose; conversions done using standard methods.
Using this, Francavilla et al [ 7] studied various doses and dosing schedules on 52 beagle dogs.
By contrast, PCV13 is similarly effective in 3-dose and 4-dose schedules versus AOM [ 45].
