Sentence examples for dose caught from inspiring English sources
But the idea that radiation's effects were directly proportional to its dose caught hold and soon was being used to predict cancer cases.
It was replaced by PCV13 in April 2010 with a two-dose catch-up for children 12 17 months of age.
This demonstration of immunogenicity and good tolerability suggests that PHiD-CV booster dose administration and 2-dose catch-up vaccination are clinically acceptable for Nigerian toddlers.
Other safety and reactogenicity measures and the immunogenicity of PHiD-CV booster dose and 2-dose catch-up vaccination were evaluated as secondary objectives.
After 2-dose catch-up vaccination, the anti-protein D antibody GMC was 501.1 EL.U/ml, an 8.1-fold increase from the pre-vaccination value (Fig. 3).
Moreover, these data suggest that immunological memory induced by primary vaccination permitted anamnestic post-booster responses with a single dose that resulted in comparable or higher responses than observed after 2-dose catch-up immunization.
This study evaluated the safety and immunogenicity of PHiD-CV when administered as a booster dose to children primed in infancy or as a 2-dose catch-up regimen to unprimed children in the second year of life.
After 2-dose catch-up, for each vaccine serotype, at least 97.1% had an antibody concentration ≥0.2 µg/ml, except for serotypes 6B (82.9%) and 23F (88.6%), and at least 91.4% had an OPA titer ≥8, except for serotypes 6B (77.4%) and 19F (85.3%).
OPA GMTs were within the same range or higher after 2-dose catch-up compared with GMTs after priming in infancy, and were consistent with post-booster GMTs for 6 vaccine serotypes and lower for the remaining 4 serotypes.
Children in the control group were offered 2-dose catch-up vaccination with PHiD-CV administered at 15 to 21 mo of age and 17 to 23 mo of age.
One month after 2-dose catch-up in the second year of life, for each vaccine pneumococcal serotype, antibody GMCs increased by 17.0- to 512.2-fold 512.2-foldaccination values.
