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D3 was not used as a loading dose because it is not available in Canada.
However, GSH conjugation may happen at any dose because it is a physiologic response to excrete "foreign bodies".
We consider 50 μL/50 μL BPA to be a low dose because it is below the LOAEL.
We selected this dose because it is approximately two hundred times higher than in serum concentration obtained in the night of proestrus in intact female rats [ 21].
The longer coverage including the upper chest contributes rather little to the dose because it is acquired normally with only one tube switched on.
The caffeine mechanisms were analyzed with that dose because it is well documented that the effect caffeine presents is dose-dependent [ 14, 29]; thus activated mechanisms are different [ 15].
Similar(53)
One ampoule of IP strength H was regarded as the maximum tolerated dose, because it was expected to cause strong local reactions [ 14, 15].
We chose 1 μg/ml as the optimal BFA dose because it was well tolerated (supplementary material Fig. S1B; Fig. 1A) and highly effective, as measured by complete GC fragmentation in hepatocytes (supplementary material Fig. S1C), enterocytes and chondrocytes (supplementary material Fig. S1D).
Residents of lower-income communities may instead miss doses because it is harder for them to get their kids to medical appointments and comply with the immunization schedule.
To estimate the daily iAs dose, all dietary doses were adjusted by the inorganic fraction before being added to the drinking water doses because it is assumed that all As present in drinking water is in the inorganic form.
We used a single dose of etoposide because it is difficult to grow sufficient numbers of fibroblasts for a dose-response curve assay.
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