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This allowed us to calculate an induction dose based on a clinical endpoint rather than an arbitrary weight-based dose.
Dosing was flexible, such that PIs could prescribe from one to four capsules per day, and could modify the dose based on a patient's symptoms and side effects.
But Medicare said there was little evidence that use of the genetic test led to better outcomes for patients compared with the existing procedure, in which doctors estimate an initial dose based on a patient's age, weight and other factors.
The Biodosimetry Assessment Tool, a software application, calculates radiation dose based on a patient's physical signs and symptoms and blood cell count analysis.
Dose painting by numbers is a voxel-level prescription of dose based on a mathematical transformation of the image intensity of individual pixels.
Despite such process variability, optimized capsomere or VLP vaccine production, using a 500-L or 1500-L ferespectivelyectively, has more than 80% chance of producing vaccine at a cost less than 1 cent per dose based on a conservative assumption of 50 μg protein per vaccine dose.
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During the in-life portion of the study (November 2003), the IDMC recommended discontinuing the 200-mg dose based on an increased frequency of musculoskeletal adverse effects.
No differences were observed between treatment groups, suggesting that clinicians can select the appropriate dose based on an individual's presentation.
Those from group OVX+BSNXD received high cholesterol chow plus 5 ml mixed row herbs (BSNXD) per kilogram body weight daily, a dosage equivalent to the human adult dose based on an established formula for human rabbit drug conversion.
The single oral dose of 200 mg empagliflozin was chosen as the supratherapeutic dose, based on an expected mean Cmax of 3490 nmol/L (~7-fold higher than the therapeutic dose) and a mean tmax of 1.8 hours in healthy volunteers [ 10].
The single oral dose of 25 mg empagliflozin is the expected daily therapeutic dose, based on an expected mean maximum plasma concentration (Cmax) of 505 nmol/L and a mean time to maximum plasma concentration (tmax) of 2.2 hours in healthy volunteers [ 10].
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