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The data discussed are mainly taken from animal models following hyperstimulation of the immune system; either by the use of very powerful adjuvants, like Freund's that are too toxic for use in practical vaccination, by deliberate high dose application of adjuvants or by the in vivo application of cytokines.
Our second aim was to evaluate the therapy response after a single dose application of this agent.
Moreover, the combination along with time and dose application of RP and compost can also affect the P-availability through mineralization and/immobilization.
Patients may benefit from a specific [177Lu]BPAMD dose application, calculated from the patients' individual uptake profile previously (pre-therapeutically) determined by [68Ga]BPAMD PET examinations.
B. bassiana strain HpA-5 was selected for dose application based on its highest mortality rate and mycosis ratio on H. postica larvae and adults at the end of screening tests.
Interestingly, the repeated low dose application regime (six times 5 mg/kg, respectively) was most effective which could be explained by prolonged in vivo drug availability.
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Now is the time to rouse them and provide water and an half-dose application of fertilizer.
High-dose application of VD (300,000 IU/kg), CH (2%) and PH (1.5%) resulted in elevated serum calcium and cholesterol levels as well as LDL/HDL ratio.
A topical formulation containing 1% (w/w) of standardized extract was prepared and used for an in vivo skin permeation study using a two-dose application.
The Tween-80-coated nanocomposite showed a wider distribution after oral administration from both repeated and single-dose application, respectively (Figures 8 and 9).
For acquiring whole-body images, SPECT/CT scanning was performed using the low-energy high-resolution collimator with a SPECT condition of continuous rotation at 6°, 10 s/view, 10 min/rotation, and a low-dose CT condition of 130 kV and 50 mAs with CARE-DOSE application (Siemens Healthcare K. K., Tokyo, Japan).
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