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As β-cell dysfunction is progressive, treatment is required, and low-dose sulphonylureas (12.5% or less of the maximum licensed dose) appear to be effective for HNF4A diabetes, 51 which is similar to the response seen with HNF1A diabetes.
Together, timing and dose appear to be essential, as Ascerbi et al. acknowledge in their letter, but there does not appear to be much consensus among current investigators regarding these two aspects (Table 1).
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The highest dose appeared to cut lung cancer incidence by two-thirds, and deaths by three-quarters.
Therefore, the transferred ozone dose appeared to be the critical parameter for the design of wastewater disinfection.
However, the 3 mg/kg dose appeared to selectively increase percentage of open arm time without affecting locomotion, suggesting that, at least in the gerbil, this is an anxiolytic-like dose.
He had become curious after using the tincture to treat nerve pain and, noticing that overstepping the advised dose appeared to have no ill-effects, decided to up his intake by a small amount each day.
Dose appears to be strongly linked to AEP total score after allowing for gender and drug (p < 0.001).
This dose appears to be safe and can be repeated after intervals of 48 h or more if there is evidence of persistent intraocular infection.
The ALC obtained after the second ipilimumab dose appears to be a particularly informative biomarker.
The dose appeared to be effective and safe for the patients.
An increase in heparin dose appeared to prevent the recurrence of white thrombi in our patient.
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CEO of Professional Science Editing for Scientists @ prosciediting.com